Key result
Lowest compared to highest education level was associated with an increased risk of incident fatal CHD or nonfatal MI (unadjusted HR 3.3, 95% CI 2.2-4.7; adjusted HR 1.9, 95% CI 1.3-2.8).
Why the study?
Does lower socioeconomic status (years of education) increase the risk of incident fatal CHD or nonfatal myocardial infarction in middle-aged women?
Population
49,259 women from Sweden aged 30-50 years at baseline from the Women's Lifestyle and Health Cohort Study
Comparison
Lower years of education, job strain, social… vs Higher years of education
Design
Cohort
Follow-up
Until the end of 2002 (approximately 10-11 years)
Authors
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Lower education associated with higher CHD/MI risk in middle-aged women; extends male data but observational design leaves causality open.
Cohort (n=49,259)
Does lower socioeconomic status (years of education) increase the risk of incident fatal CHD or nonfatal myocardial infarction in middle-aged women?
Effect estimate: HR 3.3 (95% CI 2.2-4.7)
A strong social gradient in CHD risk exists among middle-aged women, largely explained by established coronary risk factors rather than job strain or social support.
Kuper et al. (2006) conducted a cohort in Coronary Heart Disease (n=49,259). Lowest education group vs. Highest education group was evaluated on Incident fatal CHD or nonfatal myocardial infarction (HR 3.3, 95% CI 2.2-4.7). Lowest compared to highest education level was associated with an increased risk of incident fatal CHD or nonfatal MI (unadjusted HR 3.3, 95% CI 2.2-4.7; adjusted HR 1.9, 95% CI 1.3-2.8).
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