Why the study?
Does antihypertensive drug treatment reduce cardiovascular morbidity and mortality in elderly patients with hypertension?
Population
Elderly patients with hypertension, specifically mild to moderate diastolic hypertension
Comparison
Antihypertensive drug treatment vs No treatment or placebo
Design
Review
Authors
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May support treatment consideration in elderly diastolic hypertension; leaves open optimal targets and safety in frail subgroups.
Does antihypertensive drug treatment reduce cardiovascular morbidity and mortality in elderly patients with hypertension?
Treating mild to moderate diastolic hypertension in the elderly significantly reduces cardiovascular mortality, though the absolute risk reduction must be weighed against potential side effects.
William B. Applegate (1989) studied this question.