What does this research mean for the field?

Atrial fibrillation causes progressive enlargement of both the left and right atria over time in patients without other structural heart disease. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 1990CirculationOpen Access

Atrial enlargement as a consequence of atrial fibrillation. A prospective echocardiographic study.

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Why the study?

Does atrial fibrillation lead to atrial enlargement over time in patients with initially normal atrial sizes?

Population

15 patients with atrial fibrillation, initially normal atrial sizes, and no evidence of significant…

Design

Cohort

Follow-up

average 20.6 months

Authors

ASAnthony SanfilippoQueen's University VAVivian M. AbascalMount Sinai Hospital MSM SheehanHarvard University

Discussion

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Implication

AF-related biatrial enlargement should not yet change practice; leaves open whether rhythm control prevents remodeling in trials.

Structured PICO

Does atrial fibrillation lead to atrial enlargement over time in patients with initially normal atrial sizes?

Population

15 patients with atrial fibrillation, initially normal atrial sizes, and no evidence of significant structural or functional cardiac abnormalities. 12 men, 3 women, mean age 67.3 years.

Outcome

Changes in left and right atrial dimensions and volumes measured echocardiographicallysurrogate

Atrial fibrillation leads to significant progressive biatrial enlargement over time, suggesting that maintaining sinus rhythm may prevent structural remodeling.

Cite This Study

Sanfilippo et al. (1990) studied this question.

synapsesocial.com/papers/6a157cd7d64fa333899fbaba https://doi.org/10.1161/01.cir.82.3.792

Topics

Atrial fibrillation Persistent AF management Mitral valve intervention Echocardiography

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Atrial enlargement as a consequence of atrial fibrillation. A prospective echocardiographic study.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Atrial enlargement as a consequence of atrial fibrillation. A prospective echocardiographic study.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider