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To assess whether SARS-CoV-2 infection can precipitate myalgic encephalomyelitis or chronic fatigue syndrome in recovering patients.

January 18, 2021Frontiers in MedicineOpen Access

Will COVID-19 Lead to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?

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To assess whether SARS-CoV-2 infection can precipitate myalgic encephalomyelitis or chronic fatigue syndrome in recovering patients.
Literature and clinical perspective examining post-viral fatigue syndromes following viral epidemics.
Evaluation of clinical overlap between persistent post-COVID-19 symptoms and established diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome.
Infections from viral pathogens historically trigger long-term post-infectious fatigue syndromes in a subset of affected individuals.
Persistent exhaustion, cognitive impairment, and exertion intolerance following SARS-CoV-2 infection present substantial clinical parallels to myalgic encephalomyelitis.

Perspective article examines post-viral fatigue syndrome in COVID-19 survivors, highlighting the risk of chronic neuroimmune illness.

Keywords: COVID-19, SARS-CoV-2, post-infectious fatigue syndrome, post-viral fatigue syndrome, myalgic encephalomyelitis/chronic fatigue syndrome

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Komaroff et al. (2021) studied this question.

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Perspective article examines post-viral fatigue syndrome in COVID-19 survivors, highlighting the risk of chronic neuroimmune illness.

Keywords: COVID-19, SARS-CoV-2, post-infectious fatigue syndrome, post-viral fatigue syndrome, myalgic encephalomyelitis/chronic fatigue syndrome