Key result
Serum uric acid is associated with carotid intima-media thickness in asymptomatic prepubertal children, with stronger relationships in heavier children (β=0.247, P<0.001).
Why the study?
Is serum uric acid associated with carotid intima-media thickness in asymptomatic prepubertal children, and is this modulated by BMI and preperitoneal fat?
Population
359 asymptomatic prepubertal Caucasian children
Design
Cross-sectional
Authors
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Association in heavier prepubertal children warrants no practice change; leaves open causal role in early atherosclerosis and needs longitudinal confirmation.
Cross-Sectional (n=359)
Is serum uric acid associated with carotid intima-media thickness in asymptomatic prepubertal children, and is this modulated by BMI and preperitoneal fat?
p-value: p=<0.001
Higher serum uric acid is associated with increased carotid intima-media thickness in prepubertal children, an effect aggravated by higher BMI and preperitoneal fat.
Bassols et al. (2015) conducted a cross-sectional in Asymptomatic prepubertal children (n=359). Uric acid was evaluated on Association between uric acid and carotid intima-media thickness (p=<0.001). Serum uric acid is associated with carotid intima-media thickness in asymptomatic prepubertal children, with stronger relationships in heavier children (β=0.247, P<0.001).
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