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Statins for Primary Prevention in Older Adults | Synapse

November 13, 2016Open Access

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Statins for Primary Prevention in Older Adults

JGJerry H. GurwitzHeart Failure & Transplant AGAlan S. GoKaiser Permanente SFStephen P. FortmannAmerican Heart Association

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Resumen

This Viewpoint summarizes the findings and limitations of clinical trial evidence regarding the benefits and risks of statins for primary prevention of atherosclerotic cardiovascular disease in persons older than 75 years.

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Cite This Study

Gurwitz et al. (Sun,) studied this question.

synapsesocial.com/papers/6a158b8779ff98d0de4ecad8 https://doi.org/https://doi.org/10.1001/jama.2016.15212

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease2016 · 846 citations
2Muscle symptoms in statin users, associations with cytochrome P450, and membrane transporter inhibitor use: A subanalysis of the USAGE study2013 · 48 citations
3Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial2002 · 3,397 citations
4Do Statins Impair Cognition? A Systematic Review and Meta-Analysis of Randomized Controlled Trials2015 · 245 citations
5Rosuvastatin for Primary Prevention in Older Persons With Elevated C-Reactive Protein and Low to Average Low-Density Lipoprotein Cholesterol Levels: Exploratory Analysis of a Randomized Trial2010 · 267 citations