Why the study?
What are the differences in left ventricular dimensions and function between patients with malignant hypertension and severe benign hypertension?
Population
21 patients, including 13 with untreated malignant hypertension and 8 with severe benign hypertension.
Design
Cross-sectional
Authors
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Malignant hypertension may occur without hypertrophy; cross-sectional data leave open whether diastolic dysfunction precedes or follows wall changes.
What are the differences in left ventricular dimensions and function between patients with malignant hypertension and severe benign hypertension?
Malignant hypertension can present without ventricular hypertrophy, suggesting rapid onset, but is frequently associated with abnormal diastolic left ventricular function.
Shapiro et al. (1981) studied this question.
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