Key result
Fever triggers life-threatening VF in structurally normal hearts, primarily in Brugada, LQTS2, and idiopathic VF.
Why the study?
Ventricular fibrillation usually occurs in structural heart disease, but fever-induced cases have been reported in structurally normal hearts across four main associated disease categories.
Fever can trigger life-threatening ventricular fibrillation in patients with structurally normal hearts, particularly those with Brugada syndrome, LQTS-2, or idiopathic VF, warranting close surveillance and prompt antipyretic therapy.
Answers are grounded in this paper and cite their sources.
Supports fever vigilance in channelopathy patients; leaves open prospective trials to guide management.
Ventricular fibrillation (VF) is a life-threatening arrhythmia that usually happens in patients with structural heart diseases. However, fever-induced ventricular fibrillation in structurally normal hearts was reported, and the four main diseases associated with these cases were Brugada syndrome, long QT syndrome, idiopathic ventricular fibrillation, and non-cardiovascular diseases. In this review, we analyzed this phenomenon and its clinical characteristics.
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Ma et al. (2023) conducted a review in Ventricular fibrillation induced by fever in structurally normal hearts (n=31). Fever was evaluated. Fever can induce life-threatening ventricular fibrillation in patients with structurally normal hearts, primarily associated with Brugada syndrome, long QT syndrome type 2, and idiopathic ventricular fibrillation.
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