Key result
Radiologic features such as associated non-adipose masses, male sex, and thick septa increased the likelihood of well-differentiated liposarcoma by 32-, 13-, and 9-fold, respectively.
Why the study?
Do CT and MR imaging features distinguish between lipoma and well-differentiated liposarcoma in patients with fatty tumors?
Population
60 patients with histologically verified fatty tumors, 31 females and 29 males, mean age 56 years.
Design
Cohort
Authors
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Specific CT and MR imaging features, including large size, thick septa, and non-adipose masses, significantly increase the likelihood of a fatty tumor being a well-differentiated liposarcoma rather than a lipoma.
Observational (n=60)
Do CT and MR imaging features distinguish between lipoma and well-differentiated liposarcoma in patients with fatty tumors?
Effect estimate: 32-fold increase
p-value: p=<0.001
Specific CT and MR imaging features, including large size, thick septa, and non-adipose masses, significantly increase the likelihood of a fatty tumor being a well-differentiated liposarcoma rather than a lipoma.
Kransdorf et al. (2002) conducted an observational in Fatty tumors (lipoma and well-differentiated liposarcoma) (n=60). Computed tomographic (CT) and magnetic resonance (MR) imaging was evaluated on Radiologic predictors of malignancy (well-differentiated liposarcoma) (32-fold increase, p=<0.001). Radiologic features such as associated non-adipose masses, male sex, and thick septa increased the likelihood of well-differentiated liposarcoma by 32-, 13-, and 9-fold, respectively.
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