Key result
Higher frontal QRS-T angle linked to NSTEMI risk in middle-aged versus young patients.
Why the study?
The study was designed to examine the relationship between age and frontal QRS-T angle by evaluating demographic, clinical, and ECG features in patients presenting with NSTEMI.
Observational (n=396)
Frontal QRS-T angle is higher in middle-aged patients with NSTEMI compared to young patients and may serve as an independent risk marker in this population.
ÖzObjective: In this study, we aimed to examine the relationship between young and middle-aged patients and frontal QRS-T angle (FQRS-T A) by evaluating the demographic, clinical features and electrocardiographics (ECGs) of patients who presented with non-ST elevation myocardial infarction (NSTEMI). Methods:The study was planned retrospectively, and 396 patients, young age (20-45 years, n=158) and middle-aged (46-65 years, n=238) who applied to the emergency department with chest pain and were diagnosed with NSTEMI underwent coronary angiography for the first time.The FQRS-T A is calculated by the frontal plane QRS axis and the T axis (FQRS-T A=QRS-T axis) from a 12-lead plane ECG.Results: Hypertension (HT) (p<0.001) and diabetes mellitus (DM) (p<0.001),serum glucose (p=0.007),serum high-density lipoprotein cholesterol (HDL-C) level (p=0.005),SYNTAX score (p<0.001) and FQRS-T A (p<0.001) were higher in the middle-aged group.In multivariate analysis showed HT [odds ratio (OR): 4.084, 95% confidence interval (CI) (2.234-7.465),p<0.001],DM [OR: 1.452,95% CI (1.288-7.465),p=0.018], low HDL-C level [OR: 0.972, 95% CI (0.951-0.994), p=0.012],FQRS-T A [OR: 0.990, 95% CI (0.980-0.993), p<0.001], was determined as a possible independent risk factor for NSTEMI in middle-aged patients group.Analyzes showed that the optimal cut-off value for the degree of FQRS-T A to predict a middle-aged NSTEMI was >32.5%, with a sensitivity of 62% and a specificity of 52% (area under the curve: 0.633, 95% CI 0.579-0.687,p<0.001). Conclusion:In our study, FQRS-T A was found to be higher in middle-aged NSTEMI patients, and it was found to be a possible independent risk factor for NSTEMI.
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Usalp et al. (2023) conducted an observational in non-ST elevation myocardial infarction (NSTEMI) (n=396). Frontal QRS-T angle (FQRS-T A) was evaluated on FQRS-T A as an independent risk factor for NSTEMI in middle-aged patients (OR 0.990, 95% CI 0.980-0.993, p=<0.001). Frontal QRS-T angle was higher in middle-aged NSTEMI patients compared to young patients and was an independent risk factor for NSTEMI in the middle-aged group (OR 0.990; 95% CI 0.980-0.993; p<0.001).
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