Key result
Higher frontal QRS-T angle predicts ~3% greater odds of non-dipper hypertension.
Why the study?
Non-dipper hypertension is a risk factor for adverse cardiac events, and it was unknown whether frontal QRS-T angle could predict non-dipper hypertensive individuals without left ventricular hypertrophy.
Does the frontal QRS-T angle predict non-dipper status in hypertensive patients without left ventricular hypertrophy?
Observational (n=123)
Single-blind
No
Does the frontal QRS-T angle predict non-dipper status in hypertensive patients without left ventricular hypertrophy?
Odds Ratio: 1.03 (95% CI 1.02–1.06)
p-value: p=<0.001
The frontal QRS-T angle is an independent predictor of non-dipper status in hypertensive patients without left ventricular hypertrophy, offering a simple ECG marker for risk stratification.
May flag non-dipper hypertension; hypothesis-generating and requires prospective validation before clinical use.
OBJECTIVE: The frontal QRS-T angle (fQRS-T) is linked to myocardial ischemia and ventricular arrhythmias. On the other hand, non-dipper hypertension is a risk factor for cardiac adverse events. The objective of this research was to determine whether the fQRS-T, a marker of ventricular heterogeneity, could be used to predict non-dipper hypertensive individuals in the lack of left ventricular hypertrophy. METHODS: The observational study was carried out retrospectively. Patients diagnosed with hypertension were included in this study. Blood tests were routinely conducted for all patients. Electrocardiography (ECG) was conducted for each patient and echocardiography was performed. Blood pressure (BP) values were collected from the ambulatory Holter records. According to ambulatory Holter monitoring, the individuals were separated into two groups. The association between fQRS-T and hypertension was investigated. RESULTS: The research involved 123 patients, with an average age of 51.85±8.22 years, comprising 76 women (61.8%) and 47 males (38.2%). According to ambulatory Holter monitoring, patients were separated into dippers (n=65) and non-dippers (n=58). There were no statistically significant in the laboratory and echocardiographic variables (p>0.05). QT dispersion (QTd) and fQRS-T were substantially greater in the non-dipper group than in the dipper group (p=0.043 and p<0.001, respectively). Independent determinants of non-dipper status were determined by univariate and multivariate logistic regression analyses. fQRS-T was found to be the only independent indicator of non-dipper status (OR: 1.03, 95%CI: 1.02-1.06, p<0.001). CONCLUSION: The fQRS-T may be a useful marker for estimating non-dipper hypertensive individuals in the lack of left ventricular hypertrophy.
No takes yet. Share an insight, caveat, or question.
Evsen et al. (2022) conducted an observational in Hypertension (n=123). Frontal plane QRS-T angle (fQRS-T) vs. Lower fQRS-T was evaluated on Non-dipper hypertension status (OR 1.03, 95% CI 1.02-1.06, p=<0.001). An increased frontal plane QRS-T angle was an independent predictor of non-dipper hypertension (OR 1.03), with an angle >30.5 degrees predicting non-dipper status with 78.3% sensitivity and 83.4% specificity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: