Why the study?
The frontal QRS-T angle reflects depolarization and repolarization heterogeneity, and the authors investigated whether it indicates myocardial damage and predicts newly diagnosed true HT in patients with white coat hypertension.
Does the frontal QRS-T angle on surface ECG distinguish between newly diagnosed true hypertension and white coat hypertension?
Does the frontal QRS-T angle on surface ECG distinguish between newly diagnosed true hypertension and white coat hypertension?
The frontal QRS-T angle on a standard ECG is a highly sensitive and specific marker for distinguishing true hypertension from white coat hypertension.
f-QRST angle was higher in true hypertension; leaves open whether ECG aids differentiation from white coat hypertension in practice.
OBJECTIVES: The frontal QRS-T (f-QRST) angle is a measure of depolarization and repolarization heterogeneity and may be a predictor of poor ventricular health. We aimed to investigate whether the f-QRST angle indicates myocardial damage and predicts newly diagnosed true hypertension (HT) in patients with white coat hypertension. METHODS: We measured the f-QRST angle of 63 subjects with WHC and 105 patients with newly diagnosed HT. Laboratory tests and ABPM were followed up in all patients. The f-QRST angle was calculated on the surface ECGs. RESULTS: Of the patients in the study, 38.9% were female and 61.1% were male. The mean age was calculated as 59 ± 11 years. A comparison between both groups with the f-QRST angles was seen to be statistically significantly higher in the true HT group. The results of the receiving operating characteristic curve showed that the AUC value of the f-QRST angle was 0.94 (95% confidence interval, 0.91-0.97), the cutoff value was 60.5°, the sensitivity was 89.5%, and the specificity was 81%. CONCLUSION: In our study, the f-QRST angle was found to be lower in patients with WHC than in true hypertensive patients. We think that ECG, which is a simple test, can be used to distinguish between true HT and WHC.
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Akın et al. (2022) studied this question.
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