Serum Triglyceride Lipase Concentrations are Independent Risk Factors for Coronary Artery Disease and In-Stent Restenosis

Figures

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  Fig. 1.. Serum EL and HL concentrations were significantly increased in patients with CAD A, B, and C present the comparison of serum EL, HL, and LPL concentrations between controls and patients with CAD, respectively. Controls (n = 65) and CAD (n = 86). Data were median ± interquartile (IQR), Between-group comparisons were performed by Student's t-test; *P < 0.05, **P < 0.01, ***P < 0.001.

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  Fig. 2.. Combination of the three lipases provided the higher predictive power than HDL-c for CAD Receiver operating characteristic (ROC) curve was utilized to evaluate the predictive power of the three lipases and HDL-c for CAD. Empty triangles pertain to the combined three lipases together, which had the best predictive power (area under the curve (AUC) = 0.893, P < 0.001). The dashed 45-degree line is the line of non-discrimination.

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  Fig. 3.. Serum EL and HL concentrations were significantly increased in patients with instent restenosis A, B, and C present the comparison of serum EL, HL, and LPL concentrations between without and with in-stent restenosis, respectively. NO ISR (without in-stent restenosis, n = 28), ISR (with in-stent restenosis, n = 10). Data were median ± interquartile (IQR), Between-group comparisons were performed by Student's t-test; *P < 0.05; NS, not significant.

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  Fig. 4.. Serum EL concentration displayed the higher predictive power than HDL-c for in-stent restenosis Receiver operating characteristic (ROC) curve was utilized to evaluate the predictive power of the three lipases and HDL-c for in-stent restenosis. Empty squares present the EL alone, which had the best discrimination ability (area under curve (AUC) = 0.765, P < 0.001). The dashed 45-degree line is the line of non-discrimination.

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  Supplementary Fig. 1.. Serum LPL and HL concentrations were associated with the increasing number of coronary lesions The patients with CAD were divided into three groups according to the numbers of coronary lesions ((one branch lesion (n = 33), two branch lesions (n = 22), three branch lesions (n = 31)). A, B, and C present the concentrations of serum EL, HL, and LPL among one, two and three branch lesions, respectively. Data are median ± IQR; Among the three groups comparisons were performed by one-way ANOVA with LSD; *P < 0.05, **P < 0.01.