Key result
Speckle tracking detects reduced early diastolic strain rate in hypertension and diabetes correlated with BNP.
Why the study?
The study sought to analyze left ventricular function via speckle-tracking echocardiography and its correlation with BNP levels in hypertensive and diabetic patients.
Does speckle tracking imaging and BNP measurement detect subclinical left ventricular dysfunction in patients with hypertension and/or diabetes?
Systematic Review (n=601)
Does speckle tracking imaging and BNP measurement detect subclinical left ventricular dysfunction in patients with hypertension and/or diabetes?
Speckle tracking imaging and BNP levels can detect subclinical left ventricular dysfunction in patients with hypertension and/or diabetes.
Answers are grounded in this paper and cite their sources.
Speckle tracking and BNP enable earlier subclinical LV dysfunction detection in hypertension/diabetes; confirms diagnostic utility via systematic review synthesis.
The purpose of this study is to analyze diabetic and hypertensive patients who have compromised left ventricular function as determined by speckle-tracking echocardiography. These patients also had higher levels of brain natriuretic peptide (BNP), a hormone that is released by the heart in response to stress. These findings suggest that patients with diabetes and hypertension are at increased risk of developing heart failure. The systemic review included seven studies that met the inclusion criteria of patients with hypertension or diabetic hypertension, and volunteers in the control group who were normotensive, non-diabetic, and free of any cardiovascular disease. However, the quality of the included studies was generally good. This study investigated the correlation between BNP levels and left ventricular function in patients with hypertension and/or diabetes. A total of seven studies were included, with a total of 601 participants. The results revealed that in patients with hypertension and/or diabetes, there was a strong relationship between BNP levels and global systolic strain. This suggests that BNP levels may be a useful biomarker for assessing left ventricular function in these patients. This systematic review found that speckle tracking imaging could be used to detect sub-clinical changes in.LV function in patients with hypertension or diabetes. Speckle tracking imaging detected significant reductions in all patient groups compared to controls in early diastolic strain rate. All patient groups had BNP levels that were substantially greater than those of healthy controls, and BNP levels were associated with LV strain and strain rate measurements. These findings suggest that speckle tracking imaging may be a useful tool for the detection of subclinical heart failure in patients with diabetes and/or hypertension. Further research is needed to confirm the findings of this review. However, to provide accurate evidence on the use of speckle tracking imaging in patients with hypertension and/or diabetes. Future research should use larger sample sizes and more rigorous study methods.
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Elkhashab et al. (2023) conducted a systematic review in Hypertension and/or diabetes (n=601). Speckle tracking imaging and BNP measurement vs. Healthy controls was evaluated on Correlation between BNP levels and left ventricular function (global systolic strain and early diastolic strain rate). Speckle tracking imaging detected significant reductions in early diastolic strain rate in hypertensive and/or diabetic patients compared to controls, and BNP levels correlated with LV strain.
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