Inverse relationship between blood levels of high density lipoprotein subfraction 2 and magnitude of postprandial lipemia.

28 healthy volunteers (23 men, 5 women), aged 28 to 42 years, with normal fasting cholesterol and triglyceride levels, mostly within ideal body weight range, non-smokers (except one), taking no medication and with no clinical or biochemical evidence of cardiac, hepatic, renal, or endocrine disease.

Standard oral fat meal (350 ml heavy whipping cream, chocolate syrup, sugar, nonfat dry milk; 1362 calories, 86% fat, 130 g fat, 480 mg cholesterol) administered per 2 m² of body surface.

Magnitude of triglyceridemic response (measured as the area under the triglyceride curve over 8 hours or the magnitude of triglyceride increase).surrogate