In 100 patients, 3-dimensional electroanatomical mapping effectively identified incomplete lesions following pentaspline pulsed field ablation, unaffected by operator learning curve (P=0.179).
Observational (n=100)
Does 3-dimensional electroanatomical mapping effectively detect incomplete lesions following fluoroscopy-guided pentaspline pulsed field ablation in patients with atrial fibrillation?
3D electroanatomical mapping effectively identifies incomplete lesions after fluoroscopy-guided pentaspline pulsed field ablation, highlighting the limitations of relying solely on fluoroscopy in patients with anatomical variability.
p-value: p=.179
Background: Pulsed field ablation (PFA) is a novel nonthermal modality for pulmonary vein isolation (PVI) in atrial fibrillation (AF). However, the completeness of lesion formation following PFA using a pentaspline catheter remains insufficiently studied. Objective: This study aimed to evaluate the utility of 3-dimensional (3D) electroanatomical mapping in detecting incomplete lesion formation following pentaspline PFA in patients with AF. Methods: This study included 100 consecutive patients undergoing first-time PFA with the FARAWAVE™ catheter (Boston Scientific) under fluoroscopic guidance. 50 patients with paroxysmal AF underwent PVI alone, whereas 50 with persistent AF received PVI plus posterior wall isolation (PWI). Post-ablation 3D mapping was performed using the CARTO 3 system (Biosense Webster). Incomplete lesions were defined as preserved electrical activity or conduction gaps on activation or electrogram mapping. Results: = .179). Conclusion: 3D electroanatomical mapping effectively identifies incomplete lesions following pentaspline PFA. Detection rates were unaffected by operator learning curve, instead reflecting limitations of conventional guidance based primarily on fluoroscopy in patients with anatomical variability.
Yagishita et al. (Wed,) conducted a observational in Atrial fibrillation (n=100). 3-dimensional electroanatomical mapping post-pulsed field ablation was evaluated on Incomplete lesions (preserved electrical activity or conduction gaps) (p=.179). In 100 patients, 3-dimensional electroanatomical mapping effectively identified incomplete lesions following pentaspline pulsed field ablation, unaffected by operator learning curve (P=0.179).