Key result
Targeting a single activation pathway identified by the EnSite system reduced RF applications, with success linked to lower CTI conduction velocity (1.36 vs 2.17 m/s, P<0.05).
Why the study?
Does radiofrequency ablation guided by a noncontact mapping system reduce the number of RF applications required for CTI block in patients with common atrial flutter compared to conventional ablation?
Observational (n=37)
Does radiofrequency ablation guided by a noncontact mapping system reduce the number of RF applications required for CTI block in patients with common atrial flutter compared to conventional ablation?
The use of a noncontact mapping system to identify a presumed single activation pathway can reduce the number of radiofrequency applications needed to achieve CTI block in patients with common atrial flutter.
Answers are grounded in this paper and cite their sources.
May reduce RF applications during CTI ablation; leaves open whether noncontact mapping improves outcomes versus conventional approaches in randomized trials.
BACKGROUND: The functional role of the cavotricuspid isthmus (CTI) for common atrial flutter (cAFL) remains to be elucidated. In the present study, we examined whether the EnSite system (St. Jude Medical, St. Paul, MN, USA), a noncontact mapping system, is useful to evaluate the conduction properties of CTI to minimize radiofrequency (RF) ablation applications for cAFL. METHODS: We enrolled 22 consecutive patients with cAFL (64.1 ± 9.5 years old, M/F 21/1) treated with the EnSite system and examined the conduction properties during cAFL and during atrial pacing. In addition, the effectiveness of the system was evaluated in comparison with the conventional ablation group (67 ± 8.9 years old, n = 15, M/F 13/2). RESULT: In 11 out of the 22 patients, CTI block line was achieved by fewer RF applications on a presumed single activation pathway which the EnSite system showed (point ablation [PA] group), and the remaining 11 patients needed additional linear ablation (additional ablation [AA] group). The number of RF applications in the PA group was significantly smaller than that in the conventional group. During the lower lateral right atrial pacing at a cycle length of 600 ms, the CV of the CTI in the PA group was smaller compared to that in the AA group (1.36 ± 0.61 vs 2.17 ± 0.66 m/s, P < 0.05), although the CV during cAFL (averaged cycle length 245 ± 34 ms) was not different in both groups. CONCLUSIONS: These results indicate that targeting the presumed single line identified by EnSite could be an optional therapy for cAFL RF ablation, and diverse conduction properties in CTI are related to the success rate of this procedure. (PACE 2012;35:1464-1471).
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Kondo et al. (2012) conducted an observational in common atrial flutter (cAFL) (n=37). EnSite noncontact mapping system vs. Conventional ablation was evaluated on Conduction velocity of the CTI during lower lateral right atrial pacing at 600 ms (p=<0.05). Targeting a single activation pathway identified by the EnSite system reduced RF applications, with success linked to lower CTI conduction velocity (1.36 vs 2.17 m/s, P<0.05).
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