What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Healthy subjects (n=31). Intervention: MR velocity mapping. Primary outcome: Regional left ventricular long-axis velocity.

What does this research mean for the field?

MR velocity mapping reveals regional variations in left ventricular long-axis motion, with peak early-diastolic velocity being highest in the lateral wall and significantly declining with age. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 1, 1994Journal of Magnetic Resonance Imaging

Assessment of regional left ventricular long‐axis motion with MR velocity mapping in healthy subjects

Q: What question did this study set out to answer?

To evaluate the pattern and regional variability of left ventricular long-axis motion during early diastole using magnetic resonance velocity mapping.

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Key result

MR velocity mapping revealed regional variations in left ventricular long-axis motion, with peak early-diastolic velocity highest in the lateral wall (140 mm/sec) and declining with age (P<0.001).

Why the study?

Does MR velocity mapping effectively assess regional left ventricular long-axis motion in healthy subjects?

Key Points

To evaluate the pattern and regional variability of left ventricular long-axis motion during early diastole using magnetic resonance velocity mapping.
Magnetic resonance (MR) velocity mapping was performed in 31 healthy volunteers to assess long-axis motion across different myocardial regions and phases of the cardiac cycle.
Peak long-axis velocities peaked during early diastole, reaching the highest magnitude in the lateral wall (140 ± 40 mm/sec), followed by anterior (96 ± 27 mm/sec), inferior (92 ± 34 mm/sec), and inferoseptal walls (87 ± 40 mm/sec).
Peak early-diastolic velocity inversely correlated with age (r = -.64, P < .001) but showed no dependence on heart rate (r = .014, P = .94).

Study Design

Type

Cross-Sectional (n=31)

Structured PICO

Does MR velocity mapping effectively assess regional left ventricular long-axis motion in healthy subjects?

Population

31 healthy volunteers

Intervention

Magnetic resonance (MR) velocity mapping

Outcome

Pattern of left ventricular long-axis motion during early diastolesurrogate

MR velocity mapping demonstrates regional variations in left ventricular long-axis motion, with peak early-diastolic velocity declining with age.

Discussion

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Implication

May inform reference values for regional LV motion; leaves open clinical adoption pending prospective validation.

Cite This Study

Karwatowski et al. (1994) conducted a cross-sectional in Healthy subjects (n=31). MR velocity mapping was evaluated on Regional left ventricular long-axis velocity. MR velocity mapping revealed regional variations in left ventricular long-axis motion, with peak early-diastolic velocity highest in the lateral wall (140 mm/sec) and declining with age (P<0.001).

synapsesocial.com/papers/6a159b6179ff98d0de4ee161 https://doi.org/10.1002/jmri.1880040209

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Bookmark

Assessment of regional left ventricular long‐axis motion with MR velocity mapping in healthy subjects

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Assessment of regional left ventricular long‐axis motion with MR velocity mapping in healthy subjects

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider