What is the clinical evidence from this study?

Study design: Observational. Population: Mitral valve stenosis (n=15). Intervention: MR phase-shift velocity mapping. Primary outcome: Mitral and pulmonary venous flow velocity.

What does this research mean for the field?

MR phase-shift velocity mapping successfully quantifies mitral and pulmonary venous flow velocities, demonstrating a peak early diastolic mitral flow of 68 +/- 12 cm/s in healthy volunteers and correlating well with Doppler echocardiography in patients with mitral stenosis. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the feasibility and diagnostic utility of MR phase-shift velocity mapping for measuring mitral and pulmonary venous blood flow velocity patterns.

March 1, 1991Journal of Computer Assisted Tomography

MR Phase-Shift Velocity Mapping of Mitral and Pulmonary Venous Flow

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Key result

MR phase-shift velocity mapping successfully quantified flow velocities, demonstrating a peak early diastolic mitral flow of 68 +/- 12 cm/s in healthy volunteers.

Why the study?

Can MR phase-shift velocity mapping accurately measure mitral and pulmonary venous flow velocity compared to Doppler echocardiography?

Key Points

To evaluate the feasibility and diagnostic utility of MR phase-shift velocity mapping for measuring mitral and pulmonary venous blood flow velocity patterns.
Measured mitral and pulmonary venous flow velocities in 10 healthy volunteers using MR phase-shift velocity mapping.
Assessed mitral flow velocity in 5 patients with mitral valve stenosis and correlated findings with Doppler echocardiography.
Healthy volunteers exhibited peak early diastolic mitral velocity of 68 ± 12 cm/s and peak atrial contraction velocity of 39 ± 10 cm/s (early-to-late ratio 1.9 ± 0.6), whereas mitral stenosis patients showed sustained high flow velocity across diastole that correlated well with Doppler echocardiography.
Pulmonary venous flow in healthy volunteers demonstrated a peak systolic velocity of 47 ± 11 cm/s, peak diastolic velocity of 40 ± 9 cm/s, and a retrograde atrial contraction velocity of 14 ± 3 cm/s.

Study Design

Type

Observational (n=15)

Structured PICO

Can MR phase-shift velocity mapping accurately measure mitral and pulmonary venous flow velocity compared to Doppler echocardiography?

Population

10 healthy volunteers and 5 patients with mitral valve stenosis

Intervention

MR phase-shift velocity mapping

Comparator

Doppler echocardiography (in patients with mitral valve stenosis)

Outcome

Mitral and pulmonary venous flow velocitysurrogate

MR phase-shift velocity mapping is a feasible noninvasive technique for evaluating time-related flow velocity patterns and quantifying mitral and pulmonary venous blood flow velocity.

Discussion

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Implication

Supports feasibility of MR phase-shift velocity mapping for mitral flow in volunteers; leaves open validation versus Doppler echocardiography in patients.

Cite This Study

Mohiaddin et al. (1991) conducted an observational in Mitral valve stenosis (n=15). MR phase-shift velocity mapping was evaluated on Mitral and pulmonary venous flow velocity. MR phase-shift velocity mapping successfully quantified flow velocities, demonstrating a peak early diastolic mitral flow of 68 +/- 12 cm/s in healthy volunteers.

synapsesocial.com/papers/6a159b6179ff98d0de4ee169 https://doi.org/10.1097/00004728-199103000-00009

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Implication

Supports feasibility of MR phase-shift velocity mapping for mitral flow in volunteers; leaves open validation versus Doppler echocardiography in patients.

MR Phase-Shift Velocity Mapping of Mitral and Pulmonary Venous Flow

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

MR Phase-Shift Velocity Mapping of Mitral and Pulmonary Venous Flow

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider