What is the clinical evidence from this study?

Study design: Cohort. Population: Ischemic stroke (n=150). Intervention: Red cell distribution width (RDW) vs. Survivors vs. Non-survivors. Primary outcome: RDW levels at ICU output (p=<0.001).

What does this research mean for the field?

In ischemic stroke patients admitted to the ICU, elevated red cell distribution width (RDW) levels at the time of ICU output are significantly associated with higher mortality and worse prognosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 26, 2020Medicina Moderna - Modern MedicineOpen Access

Higher RDW at ICU discharge is linked to greater mortality in ischemic stroke patients.

Q: What are the key findings of this study?

In ischemic stroke patients admitted to the ICU, RDW levels at the time of ICU output were significantly higher in non-survivors compared to survivors (15.4 vs 13.6, p<0.001).

Q: What does this research mean for the field?

In ischemic stroke patients admitted to the ICU, elevated red cell distribution width (RDW) levels at the time of ICU output are significantly associated with higher mortality and worse prognosis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Why the study?

The study aimed to examine the relationship between red cell distribution width at ICU admission and discharge and mortality rates, as well as disease prognosis, in stroke patients.

Are red cell distribution width (RDW) levels associated with mortality and prognosis in ischemic stroke patients in the ICU?

Population

150 stroke patients followed in the ICU

Comparison

RDW levels at ICU input vs output and in survivors vs non-survivors

Design

Retrospective study

Key result

In ischemic stroke patients admitted to the ICU, RDW levels at the time of ICU output were significantly higher in non-survivors compared to survivors (15.4 vs 13.6, p<0.001).

Authors

HBHüseyin Büyükgöl FEFatma Eren

Discussion

Member takes

Overview

RDW at ICU discharge was associated with mortality in ischemic stroke; hypothesis-generating and requires prospective validation before clinical use.

Study Design

Type

Cohort (n=150)

Multicenter

Structured PICO

Are red cell distribution width (RDW) levels associated with mortality and prognosis in ischemic stroke patients in the ICU?

Population

150 ischemic stroke patients followed in the intensive care unit (ICU), median age 76, 46% male, single-center (Turkey). Key exclusions: non-ischemic stroke, younger than 18 years old, received blood transfusion in the ICU or in the last two weeks, admitted from other hospitals, pregnant, leukemia, myelodysplastic syndrome or tumor metastasized to the bone marrow, hematological disease.

Outcome

Mortality rates during the input and the output of the intensive care unit (ICU)hard clinical

Main Result

Absolute Event Rate: 15.4% vs 13.6%

p-value: p=<0.001

Elevated RDW levels at ICU discharge, but not at admission, are significantly associated with mortality and longer hospital stays in ischemic stroke patients.

Limitations

Retrospective study design
Single-center study
Small sample size of 150 patients

Cite This Study

Büyükgöl et al. (2020) conducted a cohort in Ischemic stroke (n=150). Red cell distribution width (RDW) vs. Survivors vs. Non-survivors was evaluated on RDW levels at ICU output (p=<0.001). In ischemic stroke patients admitted to the ICU, RDW levels at the time of ICU output were significantly higher in non-survivors compared to survivors (15.4 vs 13.6, p<0.001).

synapsesocial.com/papers/6a159f30d64fa333899fe171 https://doi.org/10.31689/rmm.2020.27.2.107

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June 26, 2020Medicina Moderna - Modern MedicineOpen Access

Higher RDW at ICU discharge is linked to greater mortality in ischemic stroke patients.

View Full Paper

Ask AI

Bookmark

Why the study?

The study aimed to examine the relationship between red cell distribution width at ICU admission and discharge and mortality rates, as well as disease prognosis, in stroke patients.

Are red cell distribution width (RDW) levels associated with mortality and prognosis in ischemic stroke patients in the ICU?

Population

150 stroke patients followed in the ICU

Comparison

RDW levels at ICU input vs output and in survivors vs non-survivors

Design

Retrospective study

Key result

In ischemic stroke patients admitted to the ICU, RDW levels at the time of ICU output were significantly higher in non-survivors compared to survivors (15.4 vs 13.6, p<0.001).

Authors

HBHüseyin Büyükgöl FEFatma Eren

Discussion

Member takes

Overview

RDW at ICU discharge was associated with mortality in ischemic stroke; hypothesis-generating and requires prospective validation before clinical use.

Study Design

Type

Cohort (n=150)

Multicenter

Structured PICO

Are red cell distribution width (RDW) levels associated with mortality and prognosis in ischemic stroke patients in the ICU?

Population

Outcome

Mortality rates during the input and the output of the intensive care unit (ICU)hard clinical

Main Result

Absolute Event Rate: 15.4% vs 13.6%

p-value: p=<0.001

Elevated RDW levels at ICU discharge, but not at admission, are significantly associated with mortality and longer hospital stays in ischemic stroke patients.

Limitations

Retrospective study design
Single-center study
Small sample size of 150 patients

Cite This Study

synapsesocial.com/papers/6a159f30d64fa333899fe171 https://doi.org/10.31689/rmm.2020.27.2.107

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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