Key result
LV pacing linked to preserved LV function and synchrony in infants with congenital complete AV block.
Why the study?
Small retrospective studies suggested left ventricular pacing may preserve LV function in children with isolated CCAVB, but prospective evaluations in neonates and infants were needed.
Does left ventricular pacing preserve LV systolic function and synchrony in neonates and infants with congenital complete atrioventricular block?
Cohort (n=20)
No
Does left ventricular pacing preserve LV systolic function and synchrony in neonates and infants with congenital complete atrioventricular block?
Left ventricular pacing in neonates and infants with congenital complete AV block preserves LV systolic function and synchrony over a 5-year follow-up, and improves EF in those with baseline dysfunction.
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LV pacing may preserve function in neonates with congenital AV block; leaves open optimal site selection pending randomized trials.
Silvetti et al. (2020) conducted a cohort in Congenital complete atrioventricular block (CCAVB) (n=20). Left ventricular pacing was evaluated on Left ventricular contractility (ejection fraction and global longitudinal strain) and synchrony. Left ventricular pacing preserved LV systolic function and synchrony over a median 60-month follow-up in 20 neonates and infants with congenital complete atrioventricular block.
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