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Sida acuta is a shrub indigenous to pantropical regions. The is widely used for its various pharmacological properties. Among of pharmacological interest occurring in the plant, are alkaloids. The aim of the present study was to the antimicrobial activity of alkaloids of S. acuta from Faso. The alkaloids had a good antimicrobial activity against test microorganisms. In the agar-well diffusion assay, highest zone diameters were recorded with Gram-positive bacteria. broth microdilution assay gave minimal inhibitory concentration ranging from 16 to 400 μg/ml and minimal bactericidal values ranging from 80 to up to 400 μg/ml. The gas -mass spectrometry analysis of the same alkaloids led to identification of cryptolepine and quindoline as the major .
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Karou et al. (2005) studied this question.
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