Key result
Vascular smooth muscle cell plasticity allows structural adaptation to biomechanical changes and may contribute to inward remodeling during strong vasoconstriction, hypertension, and flow reduction.
Smooth muscle cell plasticity allows for structural adaptation in blood vessels, potentially contributing to inward remodeling seen in hypertension.
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Informs mechanisms of vascular remodeling in hypertension; leaves open whether VSMC plasticity is a viable therapeutic target.
Tuna et al. (2011) conducted a review in Vascular remodelling. Vascular smooth muscle cell plasticity allows structural adaptation to biomechanical changes and may contribute to inward remodeling during strong vasoconstriction, hypertension, and flow reduction.
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