Key result
Repolarization time mapping identifies ablation targets in 89% of deceleration zone-related scar VTs.
Why the study?
Scar-related reentrant ventricular tachycardias involve repolarization heterogeneity as well as conduction abnormalities, but existing mapping techniques have predominantly focused on conduction delay.
Does repolarization time mapping improve the identification of ablation targets compared to conventional mapping in patients with scar-related reentrant ventricular tachycardia?
Observational (n=33)
Does repolarization time mapping improve the identification of ablation targets compared to conventional mapping in patients with scar-related reentrant ventricular tachycardia?
Repolarization time mapping identifies ablation targets in scar-related ventricular tachycardia, particularly near the exit site, complementing conventional deceleration zone mapping.
Background Ventricular tachycardias (VTs) associated with scar tissue involve reentry mechanisms influenced by both conduction abnormalities and repolarization heterogeneity. However, existing mapping techniques have predominantly focused on conduction delay. Methods This retrospective study analyzed 33 consecutive cases of catheter ablation for sustained VT. The EnSite system was employed to measure repolarization time (RT) with a high‐pass filter setting of 0.05 Hz. We compared the characteristics and concordance rates of short RT areas, defined as white or red‐colored regions, with those identified through conventional mappings in relation to ablation targets. These short RT areas were defined based on the longest interval from the QRS onset to the maximal dV / dt point of unipolar potentials, which was divided into eight equal segments. Results Out of 31 VTs across 26 cases, we found that 18 (58%) of the identified ablation targets corresponded to deceleration zones (DZs). Of them, 16 (89%) also overlapped with areas of short RTs. Notably, among the remaining 13 VTs without ablation targets corresponding to DZs, 9 (69%) had ablation targets located in areas with short RTs. The distribution analysis revealed that 84% of short RT regions were located near the exit site, whereas 75% of DZs were situated near the entrance site. The distance between the two was 16 mm (interquartile range: 6.5–27.5 mm). Conclusion This study underscored the potential of RT mapping in identifying ablation targets in scar‐related VTs. Incorporating both repolarization heterogeneity and conduction delay could significantly enhance the understanding of the intricate circuits involved in these arrhythmias.
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Kataoka et al. (2025) conducted an observational in Sustained ventricular tachycardia (n=33). Repolarization time (RT) mapping vs. Conventional mapping (deceleration zones) was evaluated on Concordance rates of short RT areas with conventional mappings in relation to ablation targets. Repolarization time mapping identified ablation targets in 89% of deceleration zone-related VTs and 69% of VTs without deceleration zone targets, highlighting its utility in scar-related VTs.
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