Key result
M-mode mitral valve measurements show no correlation with Doppler for evaluating diastolic function.
Why the study?
The study aimed to develop a reliable and easy-to-use method to evaluate diastolic function via M-mode measurement of mitral valve movement in the parasternal long axis view, similar to EPSS for systolic function.
Does M-mode measurement of mitral valve movement in the parasternal long axis view correlate with standard Doppler measurements for evaluating diastolic function in healthy volunteers?
Observational (n=30)
No
Does M-mode measurement of mitral valve movement in the parasternal long axis view correlate with standard Doppler measurements for evaluating diastolic function in healthy volunteers?
While M-mode measurement of the mitral valve in the parasternal long axis view is fast and reproducible, it does not significantly correlate with standard Doppler measurements for diastolic function in healthy volunteers.
M-mode mitral measurements should not replace Doppler for diastolic assessment in healthy volunteers; leaves open validation in clinical populations.
This pilot study aimed to develop a new, reliable, and easy-to-use method for the evaluation of diastolic function through the M-mode measurement of mitral valve (MV) movement in the parasternal long axis (PSLA), similar to E-point septal separation (EPSS) used for systolic function estimation. Thirty healthy volunteers from a tertiary emergency department (ED) underwent M-mode measurements of the MV anterior leaflet in the PSLA view. EPSS, A-point septal separation (APSS), A-point opening length (APOL), and E-point opening length (EPOL) were measured in the PSLA view, along with the E and A velocities and e' velocity in the apical four-chamber view. Correlation analyses were performed to assess the relationship between M-mode and Doppler measurements, and the measurement time was evaluated. No significant correlations were found between M-mode and Doppler measurements in the study. However, M-mode measurements exhibited high reproducibility and faster acquisition, and the EPOL value consistently exceeded the APOL value, resembling the E and A pattern. These findings suggest that visually assessing the M-mode pattern on the MV anterior leaflet in the PSLA view may be a practical approach to estimating diastolic function in the ED. Further investigations with a larger and more diverse patient population are needed to validate these findings.
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Park et al. (2023) conducted an observational in Healthy volunteers (n=30). M-mode measurement of mitral valve movement in the parasternal long axis view vs. Doppler measurements was evaluated on Correlation between M-mode and Doppler measurements. In 30 healthy volunteers, M-mode measurements of mitral valve movement in the parasternal long axis view showed no significant correlation with Doppler measurements for evaluating diastolic function.
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