Why the study?
Hypertensive patients exhibit diastolic and subclinical systolic dysfunction even in early stages, prompting the evaluation of M-Mode Apical Systolic Excursion (MMASE) to identify subclinical systolic dysfunction compared with 2D-STE LV GLS.
Does M-Mode Apical Systolic Excursion (MMASE) accurately identify subclinical systolic dysfunction compared to 2D-STE LV GLS in hypertensive patients with normal EF?
Does M-Mode Apical Systolic Excursion (MMASE) accurately identify subclinical systolic dysfunction compared to 2D-STE LV GLS in hypertensive patients with normal EF?
MMASE is a simple and useful echocardiographic tool for the early detection of subclinical LV systolic dysfunction in hypertensive patients, validated against LV GLS.
MMASE may support simpler detection of subclinical dysfunction in hypertension; leaves open whether it replaces GLS in clinical practice.
Background: Regardless of the early stages of their condition, hypertensive people exhibit diastolic and subclinical systolic dysfunction. Objective: This study aimed to evaluate the accuracy of M-Mode Apical Systolic Excursion (MMASE) to identify subclinical systolic dysfunction in hypertensive sufferers in comparison to left ventricular global longitudinal systolic strain (LV GLS) determined by 2D-Speckle tracking echocardiography (2D-STE). Patients and methods: In this case-control survey; demographics, clinical information, conventional echocardiography, tissue doppler imaging (TDI), and 2D-STE were examined in 56 hypertensive individuals with normal ejection fraction (EF), vs 28 healthy people. In order to determine MMASE. M-Mode vector was applied through the left ventricle's apex in an apical four-chamber view, and the endocardial excursion between end diastole and end systole was measured. Results: MMASE and LV GLS revealed a strong positive correlation (P< 0.001). After implementing the ROC curve in comparison to the gold standard LV GLS, we said that MMASE has a cut off value for identification of subclinical systolic dysfunction below 0.6 cm. Conclusion: In patients with hypertension, MMASE is a helpful M-mode assessment in the early diagnosis of subclinical LV systolic malfunction validated by a decrease in global LV longitudinal systolic strain.
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Yassin et al. (2022) studied this question.
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