Key result
Speckle-tracking echocardiography detects reduced GLS in hypertensive patients with LVH versus healthy controls.
Why the study?
Ejection fraction often fails to detect early left ventricular dysfunction in hypertension, whereas speckle-tracking echocardiography may provide a more sensitive assessment of subclinical myocardial strain changes.
Does 2D speckle-tracking echocardiography detect subclinical left ventricular systolic impairment in hypertensive patients with preserved ejection fraction better than conventional echocardiography?
Population
90 participants including healthy controls and hypertensive patients with or without LVH
Comparison
Hypertensive patients with LVH vs hypertensive patients without LVH vs healthy controls
Design
Cross-sectional, case-control study
Authors
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May detect subclinical systolic impairment in hypertensive LVH; leaves open superiority to conventional echocardiography and impact on outcomes.
Cross-Sectional (n=90)
No
Does 2D speckle-tracking echocardiography detect subclinical left ventricular systolic impairment in hypertensive patients with preserved ejection fraction better than conventional echocardiography?
Absolute Event Rate: -20.15% vs -24.97%
p-value: p=<0.001
2D speckle-tracking echocardiography is superior to conventional echocardiography in detecting early, subclinical left ventricular systolic dysfunction in hypertensive patients with preserved ejection fraction.
Awad et al. (2025) conducted a cross-sectional in Hypertension (n=90). Hypertension (with or without left ventricular hypertrophy) vs. Healthy controls was evaluated on Global longitudinal strain (GLS) (p=<0.001). 2D speckle-tracking echocardiography detected significantly reduced global longitudinal strain in hypertensive patients with left ventricular hypertrophy compared to healthy controls.
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