Why the study?
Hypertension is highly prevalent, and the ability of real-time three-dimensional speckle tracking echocardiography to detect early left ventricular systolic dysfunction in hypertensive patients with normal 2D systolic function needed evaluation.
Does real-time three-dimensional speckle tracking echocardiography detect early abnormalities of left ventricular systolic dysfunction in hypertensive patients with normal LV systolic function?
Does real-time three-dimensional speckle tracking echocardiography detect early abnormalities of left ventricular systolic dysfunction in hypertensive patients with normal LV systolic function?
3D speckle tracking echocardiography can detect early, subtle left ventricular systolic dysfunction in hypertensive patients who appear to have normal systolic function on standard 2D echocardiography.
May support 3D speckle tracking to detect subtle LV dysfunction in hypertension; hypothesis-generating and requires prospective validation.
Background: Hypertension is the most prevalent cardiovascular (CV) disorder, affecting 20–50% of the adult population in developed countries. Objectives: The aim of this study is to test the capability of real-time three-dimensional speckle tracking echocardiography (RT3D STE) in characterizing early abnormalities of left ventricular LV systolic dysfunction in hypertensive patients with normal LV systolic function by standard 2D echocardiography. Subjects & Methods: The study population included 150 consecutive hypertensive patients without complication and another age and sex matches 50 healthy controls. ECG, 2D and 4D echocardiography were performed for all cases. Results: There was evidence of ECG voltage criteria of LVH in about 72% of hypertensive patients which absent in healthy controls. By comparing both group there were no statistically significant difference regarding EF%, AO, ESD, EDD, EDV.ESV, while there were statistically higher significant value in the patients group regarding RWT, LVPWD, IVSD and LV mass with (P<0.001) compared to controls where there were low statistically significant higher value in the patients group regarding LA dimension and volume (P<0.05). Conclusion: 3D strain is an applicable technique; it can detect subtle or substantial changes of LV even with normal ejection fraction. The left ventricular strains (GAS, GLS and GRS) correlate negatively
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Elabbady et al. (2019) studied this question.
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