Key result
Hypertension in young patients with normal systolic function was associated with significantly worse global longitudinal strain compared to healthy controls (-19.18 vs -21.25; p=0.001).
Why the study?
The study was conducted to evaluate speckle tracking echocardiography for identifying subclinical left ventricular failure in young hypertensive individuals with normal systolic function by 2D echocardiography.
Does speckle tracking echocardiography identify subclinical left ventricular dysfunction in young hypertensive patients with normal ejection fraction compared to healthy controls?
Case-Control (n=50)
No
Does speckle tracking echocardiography identify subclinical left ventricular dysfunction in young hypertensive patients with normal ejection fraction compared to healthy controls?
Absolute Event Rate: -19.18% vs -21.25%
p-value: p=0.001
Speckle tracking echocardiography can detect subclinical left ventricular systolic dysfunction in young hypertensive patients who appear to have normal systolic function on standard 2D echocardiography.
May indicate early subclinical dysfunction; leaves open whether GLS monitoring improves outcomes in young hypertensives.
Background: Tissue Speckle Tracking examines speckle aberrations in an echo picture to determine myocardial contractility and relaxation. Reflections, refraction, and dispersion of echo beams generate speckles. Aim of the study: The purpose of this research was to use speckled tracking echocardiography to identify subclinical left ventricular failure in young hypertension individuals who had normal systolic function by 2D echocardiography. Patients and methods: The research included 30 hypertensive patients with preserved ejection fraction referred to cardiology department at AL azhar University hospital for echocardiography assessment and 20 controls. All patients were assessed clinically followed by M-Mode and 2D echocardiography assessment, pulsed wave Doppler mitral inflow as well as offline speckle tracking echocardiography. Results: Demographic data, anthropometric measurements, blood pressure measurements, conventional tissue Doppler, and strain echocardiography were compared between the two groups. Body mass index, systolic and diastolic blood pressure, left ventricular end diastolyic dimension, interventricular septal diameter, posterior wall diameter, relative wall thickness, left ventricular mass index, end diastolic volume, E/, left atrial diameter, aortic diameter, left atrial volume index, normal systolic velocity of tissue doppler mitral inflow, and GLS. The control group had a considerably greater systolic velocity (p=0.013). In comparison to the hypertension group, GLS was considerably greater in the control group (-21.25± 1.18 vs -19.18±1.66, p=0.001). Conclusion: The final result of the research recommends comprehensive longitudinal stress assessment and tissue Doppler imaging for all newly discovered arterial hypertension patients or patients with arterial hypertension who have normal ejection fraction and suffer from shortness of breath.
No takes yet. Share an insight, caveat, or question.
Allah et al. (2022) conducted a case-control in Hypertension with preserved ejection fraction (n=50). Hypertension vs. Healthy controls was evaluated on Global Longitudinal Strain (GLS) (p=0.001). Hypertension in young patients with normal systolic function was associated with significantly worse global longitudinal strain compared to healthy controls (-19.18 vs -21.25; p=0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: