Key result
2D-STE reveals subclinical systolic dysfunction in ~38% of hypertensive patients with preserved LVEF.
Why the study?
Does two-dimensional speckle tracking echocardiography detect subclinical left ventricular systolic dysfunction in hypertensive patients with preserved LVEF compared to healthy controls?
Case-Control (n=90)
Does two-dimensional speckle tracking echocardiography detect subclinical left ventricular systolic dysfunction in hypertensive patients with preserved LVEF compared to healthy controls?
Two-dimensional speckle tracking echocardiography can detect subclinical left ventricular systolic impairment in hypertensive patients who otherwise have preserved ejection fractions, potentially identifying higher-risk individuals for earlier intervention.
Answers are grounded in this paper and cite their sources.
2D-STE may flag higher-risk hypertensives with preserved LVEF; leaves open whether detection improves risk stratification or outcomes.
BACKGROUND: Early detection of subclinical left ventricular (LV) systolic dysfunction in hypertensive patients is important for the prevention of progression of hypertensive heart disease. METHODS: We studied 60 hypertensive patients (age ranged from 21 to 49 years, the duration of hypertension ranged from 1 to 18 years) and 30 healthy controls, all had preserved left ventricular ejection fraction (LVEF), detected by two-dimensional speckle tracking echocardiography (2D-STE). RESULTS: There was no significant difference between the two groups regarding ejection fraction (EF) by Simpson's method. Systolic velocity was significantly higher in the control group, and global longitudinal strain was significantly higher in the control group compared with the hypertensive group. In the hypertensive group, 23 of 60 patients had less negative global longitudinal strain than -19.1, defined as reduced systolic function, which is detected by 2D-STE (subclinical systolic dysfunction), when compared with 3 of 30 control subjects. CONCLUSION: 2D-STE detected substantial impairment of LV systolic function in hypertensive patients with preserved LVEF, which identifies higher risk subgroups for earlier medical intervention.
No takes yet. Share an insight, caveat, or question.
Ayoub et al. (2016) conducted a case-control in Hypertension with preserved LV ejection fraction (n=90). Hypertension vs. Healthy controls was evaluated on Reduced systolic function (global longitudinal strain less negative than -19.1) detected by 2D-STE. Subclinical systolic dysfunction was detected by 2D-STE in 38.3% of hypertensive patients with preserved LVEF compared to 10.0% of healthy controls.
Synapse has enriched 10 related papers. Consider them for comparative context: