What question did this study set out to answer?

To develop an algorithm using health insurance claims data to identify pregnancies, outcomes, and gestational timing, and to measure antidepressant dispensations across critical pregnancy periods.

November 1, 2016Birth Defects Research Part A Clinical and Molecular TeratologyOpen Access

Using insurance claims data to identify and estimate critical periods in pregnancy: An application to antidepressants

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Authors

EAElizabeth C. AilesCenters for Disease Control and Prevention RSRegina M. SimeoneCenters for Disease Control and Prevention ADApril L. DawsonMedical College of Wisconsin

Discussion

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Implication

Database study reveals fluctuating antidepressant dispensations across pregnancy stages in insured women, highlighting the utility of claims algorithms for pharmacoepidemiology.

Key Points

To develop an algorithm using health insurance claims data to identify pregnancies, outcomes, and gestational timing, and to measure antidepressant dispensations across critical pregnancy periods.
Analyzed inpatient and outpatient service claims from the 2013 Commercial Claims and Encounters Databases.
Developed an algorithm to assign pregnancy outcomes (live birth, stillbirth, ectopic pregnancy, induced or spontaneous abortion) and gestational age to estimate the last menstrual period, requiring ≥2 months between separate pregnancies.
Estimated the proportion of outpatient pharmacy antidepressant dispensations at various pregnancy time points.
Identified 488,887 pregnancies in 2013, with 79% culminating in a live birth.
An outpatient prescription for an antidepressant was filled in 6.2% of all pregnancies.
Antidepressant dispensations varied across pregnancy stages and dropped to their lowest level (3.1%) during the second trimester.

Cite This Study

Ailes et al. (2016) studied this question.

synapsesocial.com/papers/6a15cddda2352da34782ee63 https://doi.org/10.1002/bdra.23573

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Implication

Database study reveals fluctuating antidepressant dispensations across pregnancy stages in insured women, highlighting the utility of claims algorithms for pharmacoepidemiology.

Using insurance claims data to identify and estimate critical periods in pregnancy: An application to antidepressants

Discussion

Member takes

Implication

Key Points

Cite This Study

Using insurance claims data to identify and estimate critical periods in pregnancy: An application to antidepressants

Discussion

Member takes

Implication

Key Points

Cite This Study

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