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ACTG: AIDS Clinical Trials Group network; ALT: alanine aminotransferase; ASGPR: Asialoglycoprotein Receptor; ASO: anti-sense oligonucleotide; CAM: capsid assembly modulator; CAM-A: capsid assembly modulator with abhorrent structure; CAM-N: capsid assembly modulator with normal structure; cccDNA: covalently closed circular DNA; CHB: chronic hepatitis B; c-Raf-1/MAP: cellular Rapidly Accelerated Fibrosarcoma-1/mitogen-activated protein kinase; DR1 and DR2: direct repeat sequences 1 and 2; ETV: entecavir; FDA: Food and Drug Administration; GalNAc: N-acetylgalactosamine; HBcrAg: hepatitis B core-related antigen; HBeAg: hepatitis B e antigen; HBIG: hepatitis B immunoglobulin; HBsAg: hepatitis B surface antigen; HBV: hepatitis B virus; HBV DNA: hepatitis B virus deoxyribonucleic acid; HCC: hepatocellular carcinoma; HDV: hepatitis delta virus; ir-AE: immune-related adverse events; LNA: locked nucleic acid; MAD: multiple ascending dose; mRNA: messenger ribonucleic acid; NAPs: nucleic acid polymers; NTCP: sodium taurocholate co-transporting polypeptide; PD-1: programmed death receptor 1; PD-L1: programmed death receptor ligand 1; pgRNA: pregenomic ribonucleic acid; R-CHOP: rituximab plus cyclophosphamide plus doxorubicin plus vincristine plus prednisolone; RISC: RNA-induced silencing complex; RNAi: ribonucleic acid interference; SAD: single ascending dose; siRNA: short (small) interfering ribonucleic acid; STOPs: S-antigen traffic-inhibiting oligonucleotide polymers; TAF: tenofovir alafenamide; TDF: tenofovir disoproxil; USD: United States dollars; WHO: World Health Organization.
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Edward Gane (2020) studied this question.
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