The use of dedicated long-axis views focused on the left atrium improves the accuracy of left atrial volumes and emptying fraction measured by cardiovascular magnetic resonance
View Full Paper
Ask AI
Bookmark
Share
Key result
Dedicated LA-focused cine images eliminate the ~13 ml underestimation of LAVmax seen with standard images.
- P=0.007
- n=108
Why the study?
Routine CMR evaluation of LA volumes still uses standard LV-focused 2- and 4-chamber cine images, unlike 2D echocardiography where LA-focused views have improved accuracy.
Does the use of dedicated LA-focused long-axis views improve the accuracy of LA volumes and emptying fraction measured by CMR compared to standard LV-focused views?
Population
108 consecutive patients
Comparison
LA-focused vs standard LV-focused cine images vs short-axis cine stacks
Design
Observational comparative study
Authors
Discussion
Loading...
Member takes
Implication
May support dedicated LA-focused CMR views for accurate LA volumetry; leaves open effects on management and outcomes.
Study Design
Type
Observational (n=108)
Multicenter
Yes
Structured PICO
Does the use of dedicated LA-focused long-axis views improve the accuracy of LA volumes and emptying fraction measured by CMR compared to standard LV-focused views?
P
Population
108 consecutive adult patients undergoing clinically referred cardiovascular magnetic resonance (CMR), mean age 55, 71% male, in Italy. Key exclusions: significant cardiac arrhythmia (e.g., atrial fibrillation), congenital heart disease, heart transplantation, non-diagnostic image quality.
I
Intervention
Dedicated left atrial (LA)-focused long-axis 2- and 4-chamber cine images using cardiovascular magnetic resonance (CMR)
C
Comparator
Standard left ventricular (LV)-focused long-axis 2- and 4-chamber cine images, with manual segmentation of a short-axis cine stack covering the LA used as the reference method
O
Outcome
Accuracy of left atrial maximum volume (LAVmax), minimum volume (LAVmin), and emptying fraction (LAEF) compared to the reference short-axis methodsurrogate
Main Result
Absolute Event Rate: 83% vs 72%
p-value: p=0.007
Dedicated LA-focused long-axis CMR cine images provide more accurate measurements of left atrial volumes and emptying fraction than standard LV-focused images, without significantly increasing scan or processing time.
Limitations
- Pilot and methodological investigation without normal reference values for the proposed protocol
- Did not use an independent cardiac imaging modality (such as computed tomography) as a reference
- Purely methodological study that does not evaluate the clinical impact of the novel approach
- The biplane area-length algorithm relies on the geometric assumption of an ellipsoid chamber
Cite This Study
Tondi et al. (2023) conducted an observational in Patients undergoing clinically referred cardiovascular magnetic resonance (n=108). Left atrial-focused long-axis cine images vs. Standard left ventricular-focused long-axis cine images was evaluated on Maximum left atrial volume (LAVmax) in ml (p=0.007). Dedicated left atrial-focused long-axis cine images eliminated the underestimation of maximum left atrial volume seen with standard images (bias 0 ml vs -13 ml compared to reference).
Topics
View Full Paper
Ask AI
Bookmark
Share