Why the study?
What is the probability of graft closure in patients undergoing aortocoronary vein bypass operation?
What is the probability of graft closure in patients undergoing aortocoronary vein bypass operation?
Grafts within a patient close independently of one another during the first two years after aortocoronary vein bypass, with the probability of all grafts closing decreasing significantly as the number of grafts increases.
Graft number should inform post-CABG patency counseling; supports independent closure but leaves open durability under contemporary therapy.
A study of 540 patients who had the aortocoronary vein bypass operation (from several transplant teams) showed that grafts within a patient closed independently of one another during the first-two year postoperative period. For patients with a single vein graft, there was a 23% chance of closure during the first two year postoperative period. The chance that all grafts would close during this period for patients with two grafts was 5%, and it was 1% for patients with three grafts. The knowledge of these closure probabilities may be used by the surgeon when planning the optimal surgical maneuver.
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Alfred A. Rimm (1976) studied this question.
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