July 1, 1973Circulation
Progression of Coronary Arterial Disease After Aortocoronary Bypass Grafts
Why the study?
Does aortocoronary bypass grafting affect the progression of coronary arterial disease in grafted and nongrafted vessels?
Population
105 patients (154 grafts) undergoing aortocoronary bypass grafts
Design
Cohort
Follow-up
two weeks and one year
Authors
Discussion
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Implication
Proximal progression to occlusion after grafting warrants consideration in post-CABG surveillance; leaves open whether bypass accelerates native disease.
Key Points
- This study aims to assess the progression of coronary artery disease in patients undergoing aortocoronary bypass surgery.
- 105 patients underwent pre- and postoperative coronary angiography
- Angiographic patency assessed at two weeks and one year post-surgery
- Progression of lesions in both graft and non-graft vessels evaluated.
- 92% of grafts with proximal coronary artery stenoses occluded after two weeks
- 40% occluded after one year, with 58% remaining patent
- 13% of patients showed progression of atherosclerosis in non-grafted vessels.
Structured PICO
Does aortocoronary bypass grafting affect the progression of coronary arterial disease in grafted and nongrafted vessels?
P
Population
105 patients (154 grafts) undergoing aortocoronary bypass grafts
I
Intervention
Aortocoronary bypass grafts with pre- and postoperative coronary angiography
O
Outcome
Angiographic patency of vein grafts and progression of proximal coronary artery stenoses to occlusion at two weeks and one year after surgerysurrogate
Aortocoronary bypass grafting is associated with significant progression of proximal coronary artery stenoses to occlusion, which must be considered in postoperative assessment.
Cite This Study
Bourassa et al. (1973) studied this question.