June 1, 1978New England Journal of Medicine
Long-Term Anatomic Fate of Coronary-Artery Bypass Grafts and Functional Status of Patients Five Years after Operation
Why the study?
Does coronary-artery bypass grafting maintain long-term graft patency and symptom relief in patients with severe preoperative symptoms?
Population
n=22 patients who had undergone coronary-artery bypass grafting before 1973, had severe symptoms before…
Design
Cohort
Follow-up
53 to 84 months
Authors
Discussion
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Implication
Patent CABG grafts often remain durable long-term, yet symptom recurrence from ungrafted vessel progression warrants caution; leaves open optimal grafting strategies.
Structured PICO
Does coronary-artery bypass grafting maintain long-term graft patency and symptom relief in patients with severe preoperative symptoms?
P
Population
n=22 patients (from an initial cohort of 30 consecutive patients) who had undergone coronary-artery bypass grafting before 1973, had severe symptoms before operation, and had at least one graft patent at an early (3 to 9 months) postoperative study.
I
Intervention
Coronary-artery bypass grafting (CABG)
O
Outcome
Graft patency (assessed by coronary and graft angiography) and functional status (redevelopment of angina pectoris) at 53 to 84 months after operation
While CABG grafts that are patent early post-operation generally remain patent at 5 years, symptomatic deterioration is common due to disease progression in native ungrafted vessels.
Cite This Study
Seides et al. (1978) studied this question.