Key result
Heart rate variability indices like SDRR were increased with adverse family history (173 vs 131 ms, P=0.001) but were similar between patients with and without catastrophic events.
Why the study?
Does heart rate variability correlate with clinical features and predict catastrophic events in patients with hypertrophic cardiomyopathy?
Cohort (n=104)
Does heart rate variability correlate with clinical features and predict catastrophic events in patients with hypertrophic cardiomyopathy?
In patients with hypertrophic cardiomyopathy, heart rate variability is reduced in those with symptoms and arrhythmias but does not predict catastrophic events such as sudden death.
Answers are grounded in this paper and cite their sources.
HRV does not predict catastrophic events in HCM; leaves open its prognostic role beyond family history associations.
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Counihan et al. (1993) conducted a cohort in Hypertrophic cardiomyopathy (n=104). Heart rate variability (HRV) assessment was evaluated on Relation of HRV to markers of electrical and hemodynamic instability and catastrophic events. Heart rate variability indices like SDRR were increased with adverse family history (173 vs 131 ms, P=0.001) but were similar between patients with and without catastrophic events.
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