Lipoprotein (a) is a complex polymorphic lipoprotein whose plasma levels are primarily genetically determined by the LPA gene locus, independently of dietary or environmental factors.
Lipoprotein (a) Lp(a) is a complex polymorphic lipoprotein synthesized by the liver, which is structurally similar to low-density lipoprotein (LDL). Like the LDL molecule, Lp(a) is composed of apolipoprotein B-100 (ApoB-100) but differs in that its ApoB-100 molecule is attached to apolipoprotein (a) apo(a), a polymorphic glycoprotein not found in the LDL molecule (1). Plasma levels of Lp(a) are primarily genetically determined by the LPA gene locus, independently of dietary or environmental factors (2).
Kosmas et al. (Sun,) conducted a review in Peripheral arterial disease. Lipoprotein (a) was evaluated. Lipoprotein (a) is a complex polymorphic lipoprotein whose plasma levels are primarily genetically determined by the LPA gene locus, independently of dietary or environmental factors.