Key result
Obesity was associated with a significantly higher left ventricular mass index compared to healthy controls (95.31 vs 74.6 g/m2), but this increase did not correlate with insulin resistance.
Why the study?
Does insulin resistance correlate with increased left ventricular mass in normotensive, nondiabetic obese patients?
Population
90 subjects, age range 24 to 56 years, who were normotensive, nondiabetic, without any cardiovascular…
Comparison
Obesity (BMI >29.9 kg/m2) vs Normal weight controls (BMI <25 kg/m2)
Design
Cross-sectional
Authors
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Obesity-related LV hypertrophy occurs independently of insulin resistance in normotensive nondiabetic patients; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=90)
No
Does insulin resistance correlate with increased left ventricular mass in normotensive, nondiabetic obese patients?
Absolute Event Rate: 95.31% vs 74.6%
p-value: p=0.0001
While obese patients have higher left ventricular mass and insulin resistance than normal-weight controls, left ventricular mass does not directly correlate with insulin resistance or BMI in this normotensive, nondiabetic population.
Bulut et al. (2016) conducted a cross-sectional in Obesity (n=90). Obesity vs. Healthy controls (BMI < 25 kg/m2) was evaluated on Left ventricular mass index (LVMI) (p=0.0001). Obesity was associated with a significantly higher left ventricular mass index compared to healthy controls (95.31 vs 74.6 g/m2), but this increase did not correlate with insulin resistance.
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