Key result
Averaging global strains to create a reference strain revealed a peak shortening of -0.034 in patients with dilated cardiomyopathy and left bundle branch block compared to -0.15 in healthy controls.
Why the study?
Does comparing measured average strain to a reference strain identify measurement errors in MR-tagged ventricular mechanics in patients with discoordinate ventricular contraction?
Population
19 subjects total: 10 patients with idiopathic dilated cardiomyopathy and left bundle branch block selected…
Comparison
Measurement of ventricular mechanics using… vs Standard individual global strain measurements…
Design
Other
Authors
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May flag errors in tagged MRI strain analysis of dyssynchronous hearts; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=19)
No
Does comparing measured average strain to a reference strain identify measurement errors in MR-tagged ventricular mechanics in patients with discoordinate ventricular contraction?
Absolute Event Rate: -0.034% vs -0.15%
Averaging global strains to create a reference strain can identify significant measurement errors in MR-tagged ventricular mechanics in patients with discoordinate contraction.
Borut Kirn (2014) conducted an observational in Idiopathic dilated cardiomyopathy with left bundle branch block (n=19). Magnetic resonance (MR)-tagged imaging for reference strain calculation vs. Healthy controls was evaluated on Peak shortening for the reference strain. Averaging global strains to create a reference strain revealed a peak shortening of -0.034 in patients with dilated cardiomyopathy and left bundle branch block compared to -0.15 in healthy controls.
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