Key result
Implantable cardioverter defibrillator (ICD) leads have advanced technologically, but lead failures and the risks associated with their extraction remain an increasingly important clinical problem.
As ICD implantations increase and patient survival improves, managing ICD lead failures and the associated risks of lead extraction becomes an increasingly important clinical challenge.
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Rising ICD use heightens need for lead failure vigilance; leaves open safer extraction methods and durable lead designs.
The treatment of ventricular tachyarrhythmias has changed over the last 10 years. Implantable cardioverter defibrillators (ICDs), once used only as a last resort therapy, have now become the treatment of choice. This change occurred before the first results of randomized studies on ICD therapy in patients with life-threatening ventricular tachyarrhythmias were published by the end of 1997. Technological advances of ICD therapy, in particular the development of transvenous leads, were to a large extent responsible for this change. Modern leads are characterized by their multilumen design that incorporates straight wires and coiled conductors into a single electrode body. Conductors and insulation are sheathed with additional insulation layers. The most frequently used insulating materials are silicone, polyurethane, and fluoropolymers. Lead failures are an important complication of ICD therapy. Fractured conductors, compression, creeping, or insulation defects from abrasion can cause such lead dysfunctions. Chronically implanted leads will inevitably have an increased risk of failure due to defects despite all technological advances. In the light of improving survival figures in patients with ventricular tachyarrhythmias and increasing numbers of ICD implantations, lead failures are becoming a clinical problem of ever increasing importance. Therefore, the question of which lead types necessitate extraction when a certain failure occurs and which leads can be left in place. Despite continuous improvements in lead extraction systems and growing experience in their use, the extraction of any pacemaker or ICD lead is associated with some risk of complications.
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Gradaus et al. (2003) conducted a review in Ventricular tachyarrhythmias. Implantable cardioverter defibrillator (ICD) leads was evaluated. Implantable cardioverter defibrillator (ICD) leads have advanced technologically, but lead failures and the risks associated with their extraction remain an increasingly important clinical problem.
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