Pulmonary vein isolation using the second-generation 28-mm cryoballoon resulted in an 80% 1-year success rate for maintaining stable sinus rhythm.
Cohort (n=50)
Does pulmonary vein isolation using the second-generation 28-mm cryoballoon prevent arrhythmia recurrence in patients with paroxysmal or short-standing persistent atrial fibrillation?
The second-generation 28-mm cryoballoon for pulmonary vein isolation is effective, achieving an 80% 1-year success rate in maintaining sinus rhythm in patients with paroxysmal or short-standing persistent atrial fibrillation.
BACKGROUND: The use of second-generation cryoballoon for pulmonary vein isolation in patients with paroxysmal atrial fibrillation has demonstrated encouraging acute and mid-term results. Long-term outcome data are not yet available. METHODS AND RESULTS: Fifty patients (18 women; mean age, 61±11 years; mean left atrial diameter, 43±5 mm) with paroxysmal (36 of 50 patients; 72%) or short-standing (30 seconds excluding a 3-month blanking period. A total of 192 pulmonary veins were identified, and 191 of 192 (99%) pulmonary veins were successfully isolated. Phrenic nerve palsy occurred in 1 of 50 (2%) patients. Follow-up was available for 49 of 50 (98%) patients with a mean follow-up duration of 440±39 days. Thirty-nine of 49 (80%) patients remained in stable sinus rhythm. Of 8 of 10 patients with arrhythmia recurrence, a second procedure using radiofrequency ablation demonstrated left atrial to pulmonary vein reconduction. CONCLUSIONS: The use of second-generation 28-mm cryoballoon for pulmonary vein isolation results in an 80% 1-year success rate.
Metzner et al. (Sun,) conducted a cohort in Paroxysmal or short-standing persistent atrial fibrillation (n=50). Second-generation 28-mm cryoballoon for pulmonary vein isolation was evaluated on Stable sinus rhythm without symptomatic or documented arrhythmia episode >30 seconds (excluding a 3-month blanking period). Pulmonary vein isolation using the second-generation 28-mm cryoballoon resulted in an 80% 1-year success rate for maintaining stable sinus rhythm.