Key result
Box isolation in atrial fibrillation patients significantly decreased high-frequency heart rate variability (LnHF from 5.5 to 4.2 ms2, P<0.001) at 12 months in those without AF recurrence.
Why the study?
Does box isolation alter sympathovagal balance and prevent recurrence in patients with atrial fibrillation?
Cohort (n=92)
Does box isolation alter sympathovagal balance and prevent recurrence in patients with atrial fibrillation?
p-value: p=<0.001
Box isolation for atrial fibrillation induces long-term changes in sympathovagal balance, which may contribute to the prevention of AF recurrence.
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May indicate sympathovagal shift after box isolation in AF without recurrence; hypothesis-generating for preventing AF.
Yamaguchi et al. (2010) conducted a cohort in Atrial Fibrillation (n=92). Box isolation with non-contact mapping vs. Baseline was evaluated on Autonomic function evaluated by heart rate variability (LnHF and LF/HF ratio) (p=<0.001). Box isolation in atrial fibrillation patients significantly decreased high-frequency heart rate variability (LnHF from 5.5 to 4.2 ms2, P<0.001) at 12 months in those without AF recurrence.
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