Why the study?
Does surgical pulmonary venous isolation prevent recurrence of atrial fibrillation in patients with drug-refractory lone AF?
Does surgical pulmonary venous isolation prevent recurrence of atrial fibrillation in patients with drug-refractory lone AF?
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This study provides direct in vivo electrophysiological evidence that the pulmonary veins are critical for sustaining lone atrial fibrillation, supporting the mechanistic rationale for pulmonary vein isolation.
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Todd et al. (2003) studied this question.
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