Key result
A protocol for fractionation of heart tissue extracts myofilament proteins into a separate sample fraction based on pH solubility, enabling in-depth proteomic analysis of lower-abundance proteins.
Population
Heart tissue
Design
Preclinical
Authors
Loading...
May advance preclinical cardiac proteomics by isolating myofilament fractions; leaves open translation to human tissue.
This protocol enables more detailed proteomic analysis of heart tissue by separating highly abundant myofilament proteins from lower-abundance proteins.
Kane et al. (2006) studied Heart tissue proteomics. Myofilament protein extraction protocol was evaluated. A protocol for fractionation of heart tissue extracts myofilament proteins into a separate sample fraction based on pH solubility, enabling in-depth proteomic analysis of lower-abundance proteins.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: