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Examine the theoretical framework and clinical rationale for synchronizing brain stimulation with instantaneous endogenous brain states.

November 1, 2018Frontiers in PsychologyOpen Access

Brain State-Dependent Brain Stimulation

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Examine the theoretical framework and clinical rationale for synchronizing brain stimulation with instantaneous endogenous brain states.
Conceptual review of closed-loop paradigms integrating real-time electroencephalography with non-invasive brain stimulation techniques.
Analysis of physiological mechanisms governing how ongoing oscillatory phase and power influence cortical receptivity to external stimulation.
Targeting stimulation pulses to distinct phases of endogenous neural oscillations selectively amplifies cortical excitability and enhances synaptic plasticity.
State-dependent stimulation protocols significantly decrease response variability relative to conventional open-loop interventions delivered at arbitrary intervals.

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Implication

Opinion article demonstrates potential frameworks for state-dependent neuromodulation in human neural circuits, indicating opportunities for personalized closed-loop therapies.

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Cite This Study

Til Ole Bergmann (2018) studied this question.

synapsesocial.com/papers/6a161850284f0d689dbf94f2 https://doi.org/10.3389/fpsyg.2018.02108

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Implication

Opinion article demonstrates potential frameworks for state-dependent neuromodulation in human neural circuits, indicating opportunities for personalized closed-loop therapies.

Brain State-Dependent Brain Stimulation

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Implication

Discussion

Cite This Study

Brain State-Dependent Brain Stimulation

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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