Key result
Conduction system pacing is increasingly recognized as a superior alternative to traditional epicardial ventricular pacing in patients with a Fontan operation due to improved systolic function.
Why the study?
Does transvenous endocardial conduction system pacing improve outcomes compared to traditional epicardial pacing in patients with a Fontan operation?
Does transvenous endocardial conduction system pacing improve outcomes compared to traditional epicardial pacing in patients with a Fontan operation?
Conduction system pacing is being explored as an alternative to traditional epicardial pacing in patients with a Fontan operation to overcome challenges with scar tissue and improve electromechanical synchrony.
Ventricular pacing in patients with a Fontan operation is associated with poor outcomes.1 Moreover, delivering ventricular pacing is challenging; it is traditionally performed with epicardial leads, where dense epi-pericardial scar tissue can limit site selection for optimal electromechanical synchrony and can result in suboptimal acute lead function and decreased lead longevity. The advent of conduction system pacing (CSP) in patients with biventricular anatomy has generated a flurry of research in the past 10–20 years, leading to widespread acceptance because of superior systolic function and heart failure outcomes compared with other pacing techniques.
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Hale et al. (2025) conducted an editorial in Fontan operation requiring ventricular pacing. Transvenous endocardial conduction system pacing vs. Traditional epicardial leads was evaluated. Conduction system pacing is increasingly recognized as a superior alternative to traditional epicardial ventricular pacing in patients with a Fontan operation due to improved systolic function.
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