Key result
Echolucent atherosclerotic plaques were associated with a significantly higher risk of ischemic cerebrovascular events compared to subjects without stenosis (adjusted RR 4.6; 95% CI 1.1 to 18.9).
Why the study?
Does the presence of echolucent plaques on ultrasound predict ischemic cerebrovascular events in subjects with carotid stenosis?
Cohort (n=438)
Does the presence of echolucent plaques on ultrasound predict ischemic cerebrovascular events in subjects with carotid stenosis?
Effect estimate: RR 4.6 (95% CI 1.1 to 18.9)
p-value: p=0.015
Echolucent carotid plaques identified by ultrasound are associated with a significantly increased risk of ischemic cerebrovascular events, independent of the degree of stenosis.
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Echolucent plaques may aid risk stratification in carotid stenosis; hypothesis-generating and requires prospective validation before guiding decisions.
Mathiesen et al. (2001) conducted a cohort in Carotid stenosis (n=438). Echolucent plaques vs. Subjects without stenosis was evaluated on Ischemic cerebrovascular events (RR 4.6, 95% CI 1.1 to 18.9, p=0.015). Echolucent atherosclerotic plaques were associated with a significantly higher risk of ischemic cerebrovascular events compared to subjects without stenosis (adjusted RR 4.6; 95% CI 1.1 to 18.9).
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