Key result
Lead I R-wave amplitude ≥0.1 mV predicted left ventricular outflow tract origin of arrhythmias with 75% sensitivity, 98.2% specificity, and an AUC of 0.85.
Why the study?
Does lead I R-wave amplitude differentiate LVOT from RVOT origin in patients with LBRI pattern ventricular arrhythmias?
Cohort (n=75)
Does lead I R-wave amplitude differentiate LVOT from RVOT origin in patients with LBRI pattern ventricular arrhythmias?
Effect estimate: AUC 0.85
Lead I R-wave amplitude ≥0.1 mV is a simple and highly specific criterion for identifying LVOT origin in LBRI ventricular arrhythmias, aiding in ablation planning.
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May aid pre-procedural planning for LBRI VA ablation; hypothesis-generating and requires prospective validation before changing practice.
Xie et al. (2018) conducted a cohort in Ventricular arrhythmias with left bundle branch block right inferior axis morphology (n=75). Lead I R-wave amplitude vs. Transitional zone (TZ) index and V2S/V3R index was evaluated on Prediction of LVOT origin (AUC 0.85). Lead I R-wave amplitude ≥0.1 mV predicted left ventricular outflow tract origin of arrhythmias with 75% sensitivity, 98.2% specificity, and an AUC of 0.85.
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