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January 1, 2002HeartOpen Access

Electrophysiological characteristics and outcome in patients with idiopathic right ventricular arrhythmia compared with arrhythmogenic right ventricular dysplasia

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Key result

Electrophysiological study distinguished IRVA from ARVD, with ventricular tachycardia inducibility significantly lower in IRVA (3%) compared to ARVD (93%, p<0.0001).

Why the study?

Can a conventional electrophysiological study differentiate between patients with idiopathic right ventricular arrhythmia (IRVA) and arrhythmogenic right ventricular dysplasia (ARVD)?

Population

56 patients with a right ventricular arrhythmia and no history or signs of any cardiac disease other than…

Design

Cohort

Authors

FNFeraydoon NiroomandDiabetesinstitut HeidelbergCCCorrado CarbucicchioElectrophysiologyCTClaudio TondoElectrophysiology

Discussion

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Implication

Standard electrophysiological studies can reliably differentiate between idiopathic right ventricular arrhythmias and arrhythmogenic right ventricular dysplasia based on VT inducibility, ECG morphology, and fragmented diastolic potentials.

Study Design

Type

Observational (n=56)

Structured PICO

Can a conventional electrophysiological study differentiate between patients with idiopathic right ventricular arrhythmia (IRVA) and arrhythmogenic right ventricular dysplasia (ARVD)?

P
Population
56 patients with a right ventricular arrhythmia and no history or signs of any cardiac disease other than right ventricular dysplasia, classified as having idiopathic right ventricular arrhythmias (IRVA, n=41) or arrhythmogenic right ventricular dysplasia (ARVD, n=15).
I
Intervention
Standard diagnostic electrophysiology study
O
Outcome
Electrophysiological characteristics distinguishing IRVA from ARVD (inducibility of ventricular tachycardia, presence of more than one ECG morphology during tachycardia, and fragmented diastolic potentials)surrogate

Main Result

Absolute Event Rate: 3% vs 93%

p-value: p=<0.0001

Standard electrophysiological studies can reliably differentiate between idiopathic right ventricular arrhythmias and arrhythmogenic right ventricular dysplasia based on VT inducibility, ECG morphology, and fragmented diastolic potentials.

Cite This Study

Niroomand et al. (2002) conducted an observational in Right ventricular arrhythmia (IRVA vs ARVD) (n=56). Electrophysiological study (IRVA group) vs. ARVD group was evaluated on Inducibility of ventricular tachycardia by programmed electrical stimulation with ventricular extrastimuli (p=<0.0001). Electrophysiological study distinguished IRVA from ARVD, with ventricular tachycardia inducibility significantly lower in IRVA (3%) compared to ARVD (93%, p<0.0001).

synapsesocial.com/papers/6a163f05f508cb2fcbc1f020https://doi.org/10.1136/heart.87.1.41
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Right ventricular abnormalities in ventricular tachycardia of right ventricular origin: relation to electrophysiological abnormalities.1986 · 51 citations
  2. 2Morphological findings in apparently idiopathic ventricular tachycardia. An echocardiographic haemodynamic and histologic study1985 · 77 citations
  3. 3Right ventricular tachycardia: clinical and electrophysiologic characteristics.1983 · 392 citations
  4. 4Ten‐Years Follow‐Up of 20 Patients with Idiopathic Ventricular Tachycardia1990 · 67 citations